PUBLICATIONS
2025
2024
2023
2022
Farinre O, Anaya T, King AC, Endrias K, Hébert AH, Hill AL, Jean S, Wood JS, Ehnert S, Liang S, Laird GM, Mason RD, Roederer M, Safrit JT, Mavigner M, Chahroudi A. (2025). SIV Env RhmAbs + N-803 at ART initiation prolongs viral decay without disrupting reservoir establishment in SIV-infected infant macaques. PLoS Pathogens. 2025 Jan 10;21(1):e1012863. https://doi: 10.1371/journal.ppat.1012863.
Dankwa S, Kosman C, Dennis M, Giorgi EE, Vuong K, Pahountis I, Garza A, Binuya C, McCarthy J, Mayer BT, Ngo JT, Enemuo CA, Carnathan DG, Stanfield-Oakley S, Berendam SJ, Weinbaum C, Engelman K, Magnani DM, Chan C, Ferrari G, Silvestri G, Amara RR, Chahroudi A, Permar SR, Fouda GG, Goswami R. (2024) A novel HIV triple broadly neutralizing antibody (bNAb) combination-based passive immunization of infant rhesus macaques achieves durable protective plasma neutralization levels and mediates anti-viral effector functions. PLoS One. 2024 Nov 11;19(11):e0312411. https://doi: 10.1371/journal.pone.0312411.
Soo N, Farinre O, Chahroudi A, Boliar S, Goswami R. (2024) A gut check: understanding the interplay of the gastrointestinal microbiome and the developing immune system towards the goal of pediatric HIV remission. Retrovirology. 2024 Oct 18;21(1):15. https://doi: 10.1186/s12977-024-00648-9.
Mainou E, Berendam SJ, Obregon-Perko V, Uffman EA, Phan CT, Shaw GM, Bar KJ, Kumar MR, Fray EJ, Siliciano JM, Siliciano RF, Silvestri G, Permar SR, Fouda GG, McCarthy J, Chahroudi A, Conway JM, Chan C. (2024). Assessing the impact of autologous virus neutralizing antibodies on viral rebound time in postnatally SHIV-infected ART-treated infant rhesus macaques. Epidemics. 2024 Sep:48:100780. https://doi: 10.1016/j.epidem.2024.100780.
Chinunga TT, Chahroudi A, Ribeiro SP. (2024). Pediatric immunotherapy and HIV control. Current Opinion HIV AIDS. 2024 Jul 1;19(4):201-211. https://doi: 10.1097/COH.0000000000000857
Wagner TA, Tierney C, Huang S, Nichols S, Malee KM, Montañez NA, Coletti A, Spiegel HML, Krotje C, Bone F, Wilkins M, Abuogi L, Purswani M, Bearden A, Wiznia A, Agwu A, Chadwick EG, Richman D, Gandhi M, Mehta P, Macatangay B, Spector SA, Spudich S, Persaud D, Chahroudi A; IMPAACT2015 Protocol Team. (2024). Prevalence of detectable HIV-DNA and HIV-RNA in cerebrospinal fluid of youth with perinatal HIV and impaired cognition on antiretroviral therapy. AIDS 2024 Aug 1;38(10):1494-1504. https://doi: 10.1097/QAD.0000000000003937.
Fonseca JA, King AC, Chahroudi A. (2024) More than the Infinite Monkey Theorem: NHP Models in the Development of a Pediatric HIV Cure. Current HIV/AIDS Reports. 2024 Feb;21(1):11-29. https://doi: 10.1007/s11904-023-00686-6.
Dashti A, Sukkestad S, Horner AM, Neja M, Siddiqi Z, Waller C, Goldy J, Monroe D, Lin A, Schoof N, Singh V, Mavigner M, Lifson JD, Deleage C, Tuyishime M, Falcinelli SD, King HAD, Ke R, Mason RD, Archin NM, Dunham RM, Safrit JT, Jean S, Perelson AS, Margolis DM, Ferrari G, Roederer M, Silvestri G, Chahroudi A. (2023) AZD5582 plus SIV-specific antibodies reduce lymph node viral reservoirs in antiretroviral therapy-suppressed macaques. Nature Medicine. 2023 Oct;29(10):2535-2546. https://doi: 10.1038/s41591-023-02570-7.
Mavigner, M., & Chahroudi, A. (2023). Broadly neutralizing antibodies: "The next thing" to treat children with HIV?. Science translational medicine, 15(703), eadi0293. https://doi.org/10.1126/scitranslmed.adi0293
Tang, Y., Chaillon, A., Gianella, S., Wong, L. M., Li, D., Simermeyer, T. L., Porrachia, M., Ignacio, C., Woodworth, B., Zhong, D., Du, J., de la Parra Polina, E., Kirchherr, J., Allard, B., Clohosey, M. L., Moeser, M., Sondgeroth, A. L., Whitehill, G. D., Singh, V., Dashti, A., Smith, D. M., Eron, J. J., Bar, K. J., Chahroudi, A., … Jiang, G. (2023). Brain microglia serve as a persistent HIV reservoir despite durable antiretroviral therapy. The Journal of clinical investigation, 133(12), e167417. https://doi.org/10.1172/JCI167417
Druzak, S., Iffrig, E., Roberts, B. R., Zhang, T., Fibben, K. S., Sakurai, Y., Verkerke, H. P., Rostad, C. A., Chahroudi, A., Schneider, F., Wong, A. K. H., Roberts, A. M., Chandler, J. D., Kim, S. O., Mosunjac, M., Mosunjac, M., Geller, R., Albizua, I., Stowell, S. R., Arthur, C. M., … Maier, C. L. (2023). Multiplatform analyses reveal distinct drivers of systemic pathogenesis in adult versus pediatric severe acute COVID-19. Nature communications, 14(1), 1638. https://doi.org/10.1038/s41467-023-37269-3
Pascucci, G. R., Morrocchi, E., Pighi, C., Rotili, A., Neri, A., Medri, C., Olivieri, G., Sanna, M., Rasi, G., Persaud, D., Chahroudi, A., Lichterfeld, M., Nastouli, E., Cancrini, C., Amodio, D., Rossi, P., Cotugno, N., & Palma, P. (2023). How CD4+ T Cells Transcriptional Profile Is Affected by Culture Conditions: Towards the Design of Optimal In Vitro HIV Reactivation Assays. Biomedicines, 11(3), 888. https://doi.org/10.3390/biomedicines11030888
Perez, M. A., Hsiao, H. M., Chen, X., Kunkel, A., Baida, N., Hussaini, L., Lu, A. T., Kao, C. M., Laham, F. R., Hunstad, D. A., Beltran, Y., Hammett, T. A., Godfred-Cato, S., Chahroudi, A., Anderson, E. J., Belay, E., & Rostad, C. A. (2023). Serologic responses to COVID-19 vaccination in children with history of multisystem inflammatory syndrome (MIS-C). Vaccine, 41(17), 2743–2748. https://doi.org/10.1016/j.vaccine.2023.03.021
Archin, N., Bar, K. J., Burdo, T., Caskey, M., Chahroudi, A., Farzan, M., Ho, Y. C., Jones, R. B., Kearney, M., Kuritzkes, D., Margolis, D., Martinez-Picado, J., Okoye, A., Salgado, M., & Stevenson, M. (2023). Highlights from the Tenth International Workshop on HIV Persistence during Therapy, December 13-16, 2022, Miami, Florida-USA. Journal of virus eradication, 9(1), 100315. https://doi.org/10.1016/j.jve.2023.100315
Sass, J., Awasthi, A., Obregon-Perko, V., McCarthy, J., Lloyd, A. L., Chahroudi, A., Permar, S., & Chan, C. (2023). A simple model for viral decay dynamics and the distribution of infected cell life spans in SHIV-infected infant rhesus macaques. Mathematical biosciences, 356, 108958. https://doi.org/10.1016/j.mbs.2022.108958
Statzu, M., Jin, W., Fray, E. J., Wong, A. K. H., Kumar, M. R., Ferrer, E., Docken, S. S., Pinkevych, M., McBrien, J. B., Fennessey, C. M., Keele, B. F., Liang, S., Harper, J. L., Mutascio, S., Franchitti, L., Wang, H., Cicetti, D., Bosinger, S. E., Carnathan, D. G., Vanderford, T. H., Margolis, D. M., Garcia-Martinez, J.V., Chahroudi, A., … Silvestri, G. (2023). CD8+ lymphocytes do not impact SIV reservoir establishment under ART. Nature microbiology, 8(2), 299–308. https://doi.org/10.1038/s41564-022-01311-9
Vos, M. B., Gonzalez, M. D., Stone, C., Cleeton, R., Figueroa, J., Jerris, R., Park, S. I., Heilman, S., Nayee, R., Chahroudi, A., Schoof, N., Mavigner, M., Morris, C. R., Leong, T., Grindle, A., Westbrook, A., Lam, W., & Rogers, B. B. (2022). Comparison of Mid-turbinate Nasal Swabs, Saliva, and Nasopharyngeal Swabs for SARS-CoV-2 Reverse Transcription-Polymerase Chain Reaction Testing in Pediatric Outpatients. Archives of pathology & laboratory medicine, 146(9), 1056–1061. https://doi.org/10.5858/arpa.2021-0625-SA
Kurup, S., Burgess, R., Tine, F., Chahroudi, A., & Lee, D. L. (2022). SARS-CoV-2 Infection and Racial Disparities in Children: Protective Mechanisms and Severe Complications Related to MIS-C. Journal of racial and ethnic health disparities, 9(4), 1536–1542. https://doi.org/10.1007/s40615-021-01092-7
Bricker, K. M., Obregon-Perko, V., Williams, B., Oliver, D., Uddin, F., Neja, M., Hopkins, L., Dashti, A., Jean, S., Wood, J. S., Ehnert, S., Liang, S., Vanderford, T., Tharp, G. K., Bosinger, S. E., Schauer, A. P., Mavigner, M., Cottrell, M. L., Margolis, D., Dunham, R. M., … Chahroudi, A. (2022). Altered Response Pattern following AZD5582 Treatment of SIV-Infected, ART-Suppressed Rhesus Macaque Infants. Journal of virology, 96(7), e0169921. https://doi.org/10.1128/jvi.01699-21
Cranmer, L. M., Chung, M. H., & Chahroudi, A. (2022). Support for Establishing Best Practices for Breastfeeding in the Current HIV/ART Era. Journal of the Pediatric Infectious Diseases Society, 11(3), 90–91. https://doi.org/10.1093/jpids/piab128
Lapp, S. A., Abrams, J., Lu, A. T., Hussaini, L., Kao, C. M., Hunstad, D. A., Rosenberg, R. B., Zafferani, M. J., Ede, K. C., Ballan, W., Laham, F. R., Beltran, Y., Hsiao, H. M., Sherry, W., Jenkins, E., Jones, K., Horner, A., Brooks, A., Bryant, B., Meng, L., Hammett, T. A., Oster, M. E., Bamrah-Morris, S., Godfred-Cato, S., Belay, E., Chahroudi, A., … Rostad, C. A. (2022). Serologic and Cytokine Signatures in Children With Multisystem Inflammatory Syndrome and Coronavirus Disease 2019. Open forum infectious diseases, 9(3), ofac070. https://doi.org/10.1093/ofid/ofac070
Singh, V., Obregon-Perko, V., Lapp, S. A., Horner, A. M., Brooks, A., Macoy, L., Hussaini, L., Lu, A., Gibson, T., Silvestri, G., Grifoni, A., Weiskopf, D., Sette, A., Anderson, E. J., Rostad, C. A., & Chahroudi, A. (2022). Limited induction of SARS-CoV-2-specific T cell responses in children with multisystem inflammatory syndrome compared with COVID-19. JCI insight, 7(4), e155145. https://doi.org/10.1172/jci.insight.155145
Dashti, A., Singh, V., & Chahroudi, A. (2022). HIV Reservoirs: Modeling, Quantification, and Approaches to a Cure. Methods in molecular biology (Clifton, N.J.), 2407, 215–228. https://doi.org/10.1007/978-1-0716-1871-4_16
Dashti, A., Singh, V., & Chahroudi, A. (2022). Correction to: Designing Cure Studies in NHPs. Methods in molecular biology (Clifton, N.J.), 2407, C1. https://doi.org/10.1007/978-1-0716-1871-4_28
Berendam, S. J., Nelson, A. N., Yagnik, B., Goswami, R., Styles, T. M., Neja, M. A., Phan, C. T., Dankwa, S., Byrd, A. U., Garrido, C., Amara, R. R., Chahroudi, A., Permar, S. R., & Fouda, G. G. (2022). Challenges and Opportunities of Therapies Targeting Early Life Immunity for Pediatric HIV Cure. Frontiers in immunology, 13, 885272. https://doi.org/10.3389/fimmu.2022.885272
Ackerley, C. G., Smith, S. A., Murray, P. M., Amancha, P. K., Arthur, R. A., Zhu, Z., Chahroudi, A., Amara, R. R., Hu, Y. J., & Kelley, C. F. (2022). The rectal mucosal immune environment and HIV susceptibility among young men who have sex with men. Frontiers in immunology, 13, 972170. https://doi.org/10.3389/fimmu.2022.972170