PUBLICATIONS

2023

2022

2021

Mavigner, M., & Chahroudi, A. (2023). Broadly neutralizing antibodies: "The next thing" to treat children with HIV?. Science translational medicine, 15(703), eadi0293. https://doi.org/10.1126/scitranslmed.adi0293

Tang, Y., Chaillon, A., Gianella, S., Wong, L. M., Li, D., Simermeyer, T. L., Porrachia, M., Ignacio, C., Woodworth, B., Zhong, D., Du, J., de la Parra Polina, E., Kirchherr, J., Allard, B., Clohosey, M. L., Moeser, M., Sondgeroth, A. L., Whitehill, G. D., Singh, V., Dashti, A., Smith, D. M., Eron, J. J., Bar, K. J., Chahroudi, A., … Jiang, G. (2023). Brain microglia serve as a persistent HIV reservoir despite durable antiretroviral therapy. The Journal of clinical investigation, 133(12), e167417. https://doi.org/10.1172/JCI167417

Druzak, S., Iffrig, E., Roberts, B. R., Zhang, T., Fibben, K. S., Sakurai, Y., Verkerke, H. P., Rostad, C. A., Chahroudi, A., Schneider, F., Wong, A. K. H., Roberts, A. M., Chandler, J. D., Kim, S. O., Mosunjac, M., Mosunjac, M., Geller, R., Albizua, I., Stowell, S. R., Arthur, C. M., … Maier, C. L. (2023). Multiplatform analyses reveal distinct drivers of systemic pathogenesis in adult versus pediatric severe acute COVID-19. Nature communications, 14(1), 1638. https://doi.org/10.1038/s41467-023-37269-3

Pascucci, G. R., Morrocchi, E., Pighi, C., Rotili, A., Neri, A., Medri, C., Olivieri, G., Sanna, M., Rasi, G., Persaud, D., Chahroudi, A., Lichterfeld, M., Nastouli, E., Cancrini, C., Amodio, D., Rossi, P., Cotugno, N., & Palma, P. (2023). How CD4+ T Cells Transcriptional Profile Is Affected by Culture Conditions: Towards the Design of Optimal In Vitro HIV Reactivation Assays. Biomedicines, 11(3), 888. https://doi.org/10.3390/biomedicines11030888

Perez, M. A., Hsiao, H. M., Chen, X., Kunkel, A., Baida, N., Hussaini, L., Lu, A. T., Kao, C. M., Laham, F. R., Hunstad, D. A., Beltran, Y., Hammett, T. A., Godfred-Cato, S., Chahroudi, A., Anderson, E. J., Belay, E., & Rostad, C. A. (2023). Serologic responses to COVID-19 vaccination in children with history of multisystem inflammatory syndrome (MIS-C). Vaccine, 41(17), 2743–2748. https://doi.org/10.1016/j.vaccine.2023.03.021

Archin, N., Bar, K. J., Burdo, T., Caskey, M., Chahroudi, A., Farzan, M., Ho, Y. C., Jones, R. B., Kearney, M., Kuritzkes, D., Margolis, D., Martinez-Picado, J., Okoye, A., Salgado, M., & Stevenson, M. (2023). Highlights from the Tenth International Workshop on HIV Persistence during Therapy, December 13-16, 2022, Miami, Florida-USA. Journal of virus eradication, 9(1), 100315. https://doi.org/10.1016/j.jve.2023.100315

Sass, J., Awasthi, A., Obregon-Perko, V., McCarthy, J., Lloyd, A. L., Chahroudi, A., Permar, S., & Chan, C. (2023). A simple model for viral decay dynamics and the distribution of infected cell life spans in SHIV-infected infant rhesus macaques. Mathematical biosciences, 356, 108958. https://doi.org/10.1016/j.mbs.2022.108958

Statzu, M., Jin, W., Fray, E. J., Wong, A. K. H., Kumar, M. R., Ferrer, E., Docken, S. S., Pinkevych, M., McBrien, J. B., Fennessey, C. M., Keele, B. F., Liang, S., Harper, J. L., Mutascio, S., Franchitti, L., Wang, H., Cicetti, D., Bosinger, S. E., Carnathan, D. G., Vanderford, T. H., Margolis, D. M., Garcia-Martinez, J.V., Chahroudi, A., … Silvestri, G. (2023). CD8+ lymphocytes do not impact SIV reservoir establishment under ART. Nature microbiology, 8(2), 299–308. https://doi.org/10.1038/s41564-022-01311-9

Vos, M. B., Gonzalez, M. D., Stone, C., Cleeton, R., Figueroa, J., Jerris, R., Park, S. I., Heilman, S., Nayee, R., Chahroudi, A., Schoof, N., Mavigner, M., Morris, C. R., Leong, T., Grindle, A., Westbrook, A., Lam, W., & Rogers, B. B. (2022). Comparison of Mid-turbinate Nasal Swabs, Saliva, and Nasopharyngeal Swabs for SARS-CoV-2 Reverse Transcription-Polymerase Chain Reaction Testing in Pediatric Outpatients. Archives of pathology & laboratory medicine, 146(9), 1056–1061. https://doi.org/10.5858/arpa.2021-0625-SA

Kurup, S., Burgess, R., Tine, F., Chahroudi, A., & Lee, D. L. (2022). SARS-CoV-2 Infection and Racial Disparities in Children: Protective Mechanisms and Severe Complications Related to MIS-C. Journal of racial and ethnic health disparities, 9(4), 1536–1542. https://doi.org/10.1007/s40615-021-01092-7

Bricker, K. M., Obregon-Perko, V., Williams, B., Oliver, D., Uddin, F., Neja, M., Hopkins, L., Dashti, A., Jean, S., Wood, J. S., Ehnert, S., Liang, S., Vanderford, T., Tharp, G. K., Bosinger, S. E., Schauer, A. P., Mavigner, M., Cottrell, M. L., Margolis, D., Dunham, R. M., … Chahroudi, A. (2022). Altered Response Pattern following AZD5582 Treatment of SIV-Infected, ART-Suppressed Rhesus Macaque Infants. Journal of virology, 96(7), e0169921. https://doi.org/10.1128/jvi.01699-21

Cranmer, L. M., Chung, M. H., & Chahroudi, A. (2022). Support for Establishing Best Practices for Breastfeeding in the Current HIV/ART Era. Journal of the Pediatric Infectious Diseases Society, 11(3), 90–91. https://doi.org/10.1093/jpids/piab128

Lapp, S. A., Abrams, J., Lu, A. T., Hussaini, L., Kao, C. M., Hunstad, D. A., Rosenberg, R. B., Zafferani, M. J., Ede, K. C., Ballan, W., Laham, F. R., Beltran, Y., Hsiao, H. M., Sherry, W., Jenkins, E., Jones, K., Horner, A., Brooks, A., Bryant, B., Meng, L., Hammett, T. A., Oster, M. E., Bamrah-Morris, S., Godfred-Cato, S., Belay, E., Chahroudi, A., … Rostad, C. A. (2022). Serologic and Cytokine Signatures in Children With Multisystem Inflammatory Syndrome and Coronavirus Disease 2019. Open forum infectious diseases, 9(3), ofac070. https://doi.org/10.1093/ofid/ofac070

Singh, V., Obregon-Perko, V., Lapp, S. A., Horner, A. M., Brooks, A., Macoy, L., Hussaini, L., Lu, A., Gibson, T., Silvestri, G., Grifoni, A., Weiskopf, D., Sette, A., Anderson, E. J., Rostad, C. A., & Chahroudi, A. (2022). Limited induction of SARS-CoV-2-specific T cell responses in children with multisystem inflammatory syndrome compared with COVID-19. JCI insight, 7(4), e155145. https://doi.org/10.1172/jci.insight.155145

Dashti, A., Singh, V., & Chahroudi, A. (2022). HIV Reservoirs: Modeling, Quantification, and Approaches to a Cure. Methods in molecular biology (Clifton, N.J.), 2407, 215–228. https://doi.org/10.1007/978-1-0716-1871-4_16

Dashti, A., Singh, V., & Chahroudi, A. (2022). Correction to: Designing Cure Studies in NHPs. Methods in molecular biology (Clifton, N.J.), 2407, C1. https://doi.org/10.1007/978-1-0716-1871-4_28

Berendam, S. J., Nelson, A. N., Yagnik, B., Goswami, R., Styles, T. M., Neja, M. A., Phan, C. T., Dankwa, S., Byrd, A. U., Garrido, C., Amara, R. R., Chahroudi, A., Permar, S. R., & Fouda, G. G. (2022). Challenges and Opportunities of Therapies Targeting Early Life Immunity for Pediatric HIV Cure. Frontiers in immunology, 13, 885272. https://doi.org/10.3389/fimmu.2022.885272

Ackerley, C. G., Smith, S. A., Murray, P. M., Amancha, P. K., Arthur, R. A., Zhu, Z., Chahroudi, A., Amara, R. R., Hu, Y. J., & Kelley, C. F. (2022). The rectal mucosal immune environment and HIV susceptibility among young men who have sex with men. Frontiers in immunology, 13, 972170. https://doi.org/10.3389/fimmu.2022.972170

Obregon-Perko, V., Bricker, K. M., Mensah, G., Uddin, F., Rotolo, L., Vanover, D., Desai, Y., Santangelo, P. J., Jean, S., Wood, J. S., Connor-Stroud, F. C., Ehnert, S., Berendam, S. J., Liang, S., Vanderford, T. H., Bar, K. J., Shaw, G. M., Silvestri, G., Kumar, A., Fouda, G. G., … Chahroudi, A. (2021). Dynamics and origin of rebound viremia in SHIV-infected infant macaques following interruption of long-term ART. JCI insight, 6(23), e152526. https://doi.org/10.1172/jci.insight.152526

Kuypers, F. A., Rostad, C. A., Anderson, E. J., Chahroudi, A., Jaggi, P., Wrammert, J., Mantus, G., Basu, R., Harris, F., Hanberry, B., Camacho-Gonzalez, A., Manoranjithan, S., Vos, M., Brown, L. A., & Morris, C. R. (2021). Secretory phospholipase A2 in SARS-CoV-2 infection and multisystem inflammatory syndrome in children (MIS-C). Experimental biology and medicine (Maywood, N.J.), 246(23), 2543–2552. https://doi.org/10.1177/15353702211028560

Babiker, A., Immergluck, K., Stampfer, S. D., Rao, A., Bassit, L., Su, M., Nguyen, V., Stittleburg, V., Ingersoll, J. M., Bradley, H. L., Mavigner, M., Schoof, N., Kraft, C. S., Chahroudi, A., Schinazi, R. F., Martin, G. S., Piantadosi, A., Lam, W. A., & Waggoner, J. J. (2021). Single-Amplicon Multiplex Real-Time Reverse Transcription-PCR with Tiled Probes To Detect SARS-CoV-2 spike Mutations Associated with Variants of Concern. Journal of clinical microbiology, 59(12), e0144621. https://doi.org/10.1128/JCM.01446-21

Ravichandran, S., Tang, J., Grubbs, G., Lee, Y., Pourhashemi, S., Hussaini, L., Lapp, S. A., Jerris, R. C., Singh, V., Chahroudi, A., Anderson, E. J., Rostad, C. A., & Khurana, S. (2021). SARS-CoV-2 immune repertoire in MIS-C and pediatric COVID-19. Nature immunology, 22(11), 1452–1464. https://doi.org/10.1038/s41590-021-01051-8

Roback, J. D., Tyburski, E. A., Alter, D., Asakrah, S., Chahroudi, A., Esper, A., Farmer, S., Figueroa, J., K Frediani, J., D Gonzalez, M., S Gottfried, D., Guarner, J., A Gupta, N., S Heilman, S., E Hill, C., Jerris, R., R Kempker, R., Ingersoll, J., Levy, J. M., Mavigner, M., … Lam, W. A. (2021). The need for new test verification and regulatory support for innovative diagnostics. Nature biotechnology, 39(9), 1060–1062. https://doi.org/10.1038/s41587-021-01047-7

Bricker, K. M., Chahroudi, A., & Mavigner, M. (2021). New Latency Reversing Agents for HIV-1 Cure: Insights from Nonhuman Primate Models. Viruses, 13(8), 1560. https://doi.org/10.3390/v13081560

Frediani, J. K., Levy, J. M., Rao, A., Bassit, L., Figueroa, J., Vos, M. B., Wood, A., Jerris, R., Van Leung-Pineda, Gonzalez, M. D., Rogers, B. B., Mavigner, M., Schinazi, R. F., Schoof, N., Waggoner, J. J., Kempker, R. R., Rebolledo, P. A., O'Neal, J. W., Stone, C., Chahroudi, A., … Lam, W. A. (2021). Multidisciplinary assessment of the Abbott BinaxNOW SARS-CoV-2 point-of-care antigen test in the context of emerging viral variants and self-administration. Scientific reports, 11(1), 14604. https://doi.org/10.1038/s41598-021-94055-1

Rees, C. A., Rostad, C. A., Mantus, G., Anderson, E. J., Chahroudi, A., Jaggi, P., Wrammert, J., Ochoa, J. B., Ochoa, A., Basu, R. K., Heilman, S., Harris, F., Lapp, S. A., Hussaini, L., Vos, M. B., Brown, L. A., & Morris, C. R. (2021). Altered amino acid profile in patients with SARS-CoV-2 infection. Proceedings of the National Academy of Sciences of the United States of America, 118(25), e2101708118. https://doi.org/10.1073/pnas.2101708118

Chahroudi, A., & Permar, S. (2021). Will We Have the Tools to Address a Reemergent Zika Virus Epidemic?. Annals of internal medicine, 174(5), 708–709. https://doi.org/10.7326/M21-0397

Wood, M. P., Jones, C. I., Lippy, A., Oliver, B. G., Walund, B., Fancher, K. A., Fisher, B. S., Wright, P. J., Fuller, J. T., Murapa, P., Habib, J., Mavigner, M., Chahroudi, A., Sather, D. N., Fuller, D. H., & Sodora, D. L. (2021). Rapid progression is associated with lymphoid follicle dysfunction in SIV-infected infant rhesus macaques. PLoS pathogens, 17(5), e1009575. https://doi.org/10.1371/journal.ppat.1009575

Singh, V., Dashti, A., Mavigner, M., & Chahroudi, A. (2021). Latency Reversal 2.0: Giving the Immune System a Seat at the Table. Current HIV/AIDS reports, 18(2), 117–127. https://doi.org/10.1007/s11904-020-00540-z

Mavigner, M., Liao, L. E., Brooks, A. D., Ke, R., Mattingly, C., Schoof, N., McBrien, J., Carnathan, D., Liang, S., Vanderford, T. H., Paiardini, M., Kulpa, D., Lifson, J. D., Dunham, R. M., Easley, K. A., Margolis, D. M., Perelson, A. S., Silvestri, G., & Chahroudi, A. (2021). CD8 lymphocyte depletion enhances the latency reversal activity of the SMAC mimetic AZD5582 in ART-suppressed SIV-infected rhesus macaques. Journal of virology, 95(8), e01429-20. https://doi.org/10.1128/JVI.01429-20

George, P. E., Stokes, C. L., Bassit, L. C., Chahroudi, A., Figueroa, J., Griffiths, M. A., Heilman, S., Ku, D. N., Nehl, E. J., Leong, T., Levy, J. M., Kempker, R., Mannino, R. G., Mavigner, M., Park, S. I., Rao, A., Rebolledo, P. A., Roback, J. D., Rogers, B. B., Schinazi, R. F., … Lam, W. A. (2021). Covid-19 will not "magically disappear": Why access to widespread testing is paramount. American journal of hematology, 96(2), 174–178. https://doi.org/10.1002/ajh.26059

Berendam, S. J., Styles, T. M., Morgan-Asiedu, P. K., Tenney, D., Kumar, A., Obregon-Perko, V., Bar, K. J., Saunders, K. O., Santra, S., De Paris, K., Tomaras, G. D., Chahroudi, A., Permar, S. R., Amara, R. R., & Fouda, G. G. (2021). Systematic Assessment of Antiviral Potency, Breadth, and Synergy of Triple Broadly Neutralizing Antibody Combinations against Simian-Human Immunodeficiency Viruses. Journal of virology, 95(3), e01667-20. https://doi.org/10.1128/JVI.01667-20

Raper, J., & Chahroudi, A. (2021). Clinical and Preclinical Evidence for Adverse Neurodevelopment after Postnatal Zika Virus Infection. Tropical medicine and infectious disease, 6(1), 10. https://doi.org/10.3390/tropicalmed6010010

Li, M., Brokaw, A., Furuta, A. M., Coler, B., Obregon-Perko, V., Chahroudi, A., Wang, H. Y., Permar, S. R., Hotchkiss, C. E., Golos, T. G., Rajagopal, L., & Adams Waldorf, K. M. (2021). Non-human Primate Models to Investigate Mechanisms of Infection-Associated Fetal and Pediatric Injury, Teratogenesis and Stillbirth. Frontiers in genetics, 12, 680342. https://doi.org/10.3389/fgene.2021.680342

Tuyishime, M., Dashti, A., Faircloth, K., Jha, S., Nordstrom, J. L., Haynes, B. F., Silvestri, G., Chahroudi, A., Margolis, D. M., & Ferrari, G. (2021). Elimination of SHIV Infected Cells by Combinations of Bispecific HIVxCD3 DART® Molecules. Frontiers in immunology, 12, 710273. https://doi.org/10.3389/fimmu.2021.710273

Amin, O., Powers, J., Bricker, K. M., & Chahroudi, A. (2021). Understanding Viral and Immune Interplay During Vertical Transmission of HIV: Implications for Cure. Frontiers in immunology, 12, 757400. https://doi.org/10.3389/fimmu.2021.757400

Lapp, S. A., Edara, V. V., Lu, A., Lai, L., Hussaini, L., Chahroudi, A., Anderson, L. J., Suthar, M. S., Anderson, E. J., & Rostad, C. A. (2021). Original antigenic sin responses to Betacoronavirus spike proteins are observed in a mouse model, but are not apparent in children following SARS-CoV-2 infection. PloS one, 16(8), e0256482. https://doi.org/10.1371/journal.pone.0256482